Artificial heart muscle, an innovative artificial device capable of replicating the functionality of the human heart.
BIOVARIA: CANDIDATE TECHNOLOGIES
BioVaria is the European “business – matching” event in the field of Life Sciences, online from 11 to 12 May 2022. An event that offers the institutions associated with Netval the opportunity to meet companies and investors to form partnerships and compare his own research with international colleagues.
Here are the technologies that have applied this year from our University and IRCCS network.
Terapia basata sull'uso di derivati antibiotici per il trattamento di melanoma, cancro al colon-retto, prostata, seno e polmoni.
Fenoldopam for the treatment of haemolytic uremic syndrome from disease diagnosis to renal functional recovery.
Fabric for splits and braces, which adapts to the curves and then stiffens, with characteristics comparable to a rigid / plaster brace.
Sterilizer of medical waste and infectious risk materials, able to move in the waste production workplaces.
Purification of mAbs and their fragments from impure mixtures via crystallisation and/or precipitation assisted by artificial membranes.
Novel implantable device for the treatment of tricuspid valve regurgitation and ventricular heart remodelling.
VibroFect is an innovative technology for preparing particles for transfection in a reproducible and controlled way.
Insulin intake device capable of measuring the injection angle, recognising the anatomical site, and detecting the dose.
Formulation comprising R-Ketorolac, Bumetadine, a Cl channel blocker and Infliximab with antiepileptic effect on neuronal circuits.
DNA aptamers capable of masking the binding site of SAR-CoV-2 to the cell and block the spread of the coronavirus.
Palladium compounds with vinyl or butadienyl fragments, having a strong antiproliferative activity on various tumor cell types.
Specific amino acids that normalize the functioning of the hepatic estrogen receptor for pathologies associated with post-menopause.
Compound 1-piperidine propionic acid as an adjuvant in the treatment of several types of solid tumors that overexpress SerpinB3.
Device able to perform three-dimensional movements of the limbs in an interactive way and monitor the physical / biometric parameters.
Engineering of cell cultures for drug screening and for the study of the mechanisms underlying the onset of diseases.
New compounds capable of acting on PCSK9, a different biological target for the treatment of hypercholesterolemia.
Preparation procedure for the use of scleral ossicles for bone regeneration, to be introduced into 3D scaffolds.
Creation of assemblies with one or more molecules and a conventional antibiotic, to enhance the antimicrobial activity of an antibiotic.
Use of SIRT1 enzyme’s inhibitors or antagonists for the prevention and/or treatment of diseases induced by human papillomavirus (HPV).
Pharmaceutical product for the treatment of all forms of ALS by acting on the dysregulation of miR-129-1 in patients with familial or sporadic ALS.
Device for preserving the vitality of the vessel during a coronary artery bypass graft by optimizing the exchange of nutrients and oxygen.
Use of a mixture consisting of modulators to slow down muscle atrophy, a highly debilitating condition characterized by loss of skeletal muscle mass.
MALDI-MS-Imaging method to solve "indeterminate due to malignancy" (TIR3) and "suspected" (TIR4) cases for more precise diagnoses.
The aim of this invention is the use of myelin nanovesicles (MyVes) in multiple sclerosis (MS) or in Central Nervous System (CNS) diseases. In particular, MyVes could be relevant [...]
Peptides and peptidomimetics for the inhibition of protein-protein interactions of the SHP2 phosphatase, for treatmenting various neoplasms and RASopathies.
Nano-transducer capable of modifying a target genomic sequence in a cell, in order to cancel harmful mutations at the basis of genetic diseases.
Thermal patch with polymeric films loaded with non-toxic nanoparticles capable of efficiently converting absorbed (red) light into heat.
Nanoparticles for the treatment of acute and chronic pain to minimize the painkillers and antipsychotics' serious side effects.
First inhibitory compounds of the MAGL enzyme with reversible action, to treat pathologies like sclerosis, Alzheimer, tumors with lower side effects.
MC4R antagonist formulation for the treatment of solid tumors such as melanoma, tumors of the gastrointestinal tract and thyroid carcinoma.
Therapeutic treatment of chromatinopathies, i.e. genetic dis-orders characterized by mutated genes encoding for chromatin regulators.
Non invasive method to evaluate brain heat flow with magnetic resonance imaging for monitoring and diagnostic purposes.
Isolation of extracellular vesicles from plasma of cancer patients and the use of isolated vesicles for the administration of drugs.
Direct labelling allowing the early diagnosis of several pathologies, thanks to the conjugation of the chelators with sensible biomolecules.
Method to measure the concentration of the drug Imatinib in patient's plasma and then to establish the optimal dose for his therapy.
Anti-HIV agents with a very low degree of toxicity, suitable for a prolonged therapeutic treatment and able to contain the resistant forms of the virus.
Molecules for the treatment of rare genetic muscular diseases that tanks to correctors allows the involved protein to retain its correct structure.
Endoprosthesis developed to reduce the risk of endoleaks and embolusthat that allows a less invasive endovascular surgical approach.
Compound useful to reduce tissue damage and for the development of effective drug treatments for hepatic, rheumatic and pneumological diseases.
3-D co-culture method of podocytes and endothelial cells for in vitro model study of pathologies affecting kidney