Titanium surfaces for bone integration
Multifunctional Titanium surfaces MimeTi, favor the bone integration of orthopedic and dental implants increasing the production of both the mineral component and the organic matrix of bone. MimeTi-plus surfaces are specifically intended to actively fight infection development without the employment of antibiotics (addition of an inorganic antibacterial agent) while maintaining all MimeTi features.
MimeTi allows the in-vivo precipitation of natural hydroxyapatite nano-crystals directly on the implant: the bioactive metal enables the biomineralization process, attracting calcium ions and phosphate groups from body fluids. At the same time, the surface stimulates faster adhesion and differentiation of osteoblasts, promoting the organic matrix deposition. The resulting bone-device integration is more rapid and stable. Thus, the metal surface presents excellent osteoinductive and osteoconductive properties. MimeTi-plus reduces bacterial adhesion in a significant way. The absence of coatings or crystalline synthetic deposits allows a direct contact between the regenerated bone and the implant, avoiding the risk of both detachment and formation of weak interfaces. Biomolecules, with antibacterial or anti-inflammatory actions can be grafted onto the surface for a physiological response.
- Prosthetic devices;
- Dental implants;
- Fixation screws;
- Spinal devices.
- Biomimetic metal;
- Multi-scale roughness;
- Improved corrosion resistance;
- Unaltered properties after sterilization/storage;
- Rapid process (<4h), no expensive equipment;
- Antibacterial action, no antibiotics.