STRAWBERRIES EXTRACT FOR UTERINE LEIOMYOMAS
The invention belongs to the field of treatment of uterine leiomyomas (fibroids).
It proposes the usage of specific strawberry extracts for the prevention, treatment, and progression control of uterine fibroids. It is based on a specific cultivar of strawberries selected for its high antioxidant capacity and high content of phenols and anthocyanins.
Leiomyomas are benign tumors of the uterine musculature characterized by fibrosis.
They affect 25% of women of childbearing age, can become large and/or numerous, with devastating symptoms (painful menstruation, anemia, swelling, infertility). To date, the treatment remains surgical, partial (myectomy) or even total (hysterectomy), while medical treatment is mostly hormonal with several side effects and with limited use over time.
The extracts of some strawberry cultivars reduce the concentration of free radicals (ROS) and improve glucose metabolism in myometrium cells (healthy cells of the uterine muscle), while they have cytotoxic effect (increase in cell death and level of intracellular ROS, worsening glucose metabolism) and antifibrotic effect in leiomyoma cells (fibrotic tumor mass cells).
- Pharmaceutical industry;
- Prevention, control, and treatment of leiomyoma (fibroids).
- Usage of natural substances;
- Positive effect on healhty tissues (myometrium);
- Negative effect on sick tissues (leiomyoma);