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Solid-liquid multivariable extractor – SoLVE

estrazioneextractiongreen solventspurficationPurificazionethermosensitive moleculesultrasounds


The proposed invention allows to use several operating parameters and configurations for the extraction of molecules from solid matrices and solid-liquid separation, simultaneously. This technology is particularly suitable for the recovery of thermosensitive molecules and is proposed as equipment for research and development in academic and industrial laboratories.

Technical features

SoLVE (SOlid-Liquid multiVariable Extractor) is a new extraction technique using a packed-bed system, high pressure and temperatures, assisted by ultrasounds and heat exchangers located in several zone of the plant for heating or cooling, depending on the needs. Currently, various kind of devices are available on the market that can operate non-conventional extractions such as: microwave-assisted extractors, ultrasound-assisted extractors, extractors operating under high pressures and / or high temperatures (under sub or supercritical conditions). Such technologies allow the use of one or sometimes two additional operating parameters compared to the conventional solid liquid extraction to increase process yields. The innovation of SoLVE technology is to operate individually or simultaneously with a multiplicity of parameters, so resulting extremely versatile and adaptable to different matrices and molecules of interest for research and industry. SoLVE can work on temperature, pressure, ultrasounds and solvent gradient, being able to mix more solvents and change their composition over time. This versatility is due to the possibility of setting different operating parameters able to increase the selectivity towards specific molecules (es. polyphenols, lipo- and hydrosoluble vitamins, proteins, etc.). In addition, the proposed technology finds potential application in the purification of polluted solid materials (e.g. exhausted catalysts) or for the removal of undesired molecules from complex matrices (e.g. heavy metals). These features make the technology particularly attractive for food, cosmetic, chemical and environmental sectors.

Possible Applications

  • Extraction of molecules of interest to the food, cosmetic and pharmaceutical industries;
  • Regeneration of exhausted catalysts;
  • Purification of polluted particulate materials;
  • Study of the effect of different operating parameters for research.


  • Possibility to use different configurations and to work on different parameters;
  • Simultaneous extraction and filtration;
  • Safety in handling solvents.
  • Reduction of dead and process times.