Politecnico di Torino - Corso Duca degli Abruzzi, 24 - 10129 Torino, ITALY

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PROTEIN SCAFFOLD FOR CELLULAR DIFFERENTIATION

Differentiationneural networksNeuronesPeroxredoxinScaffold

Introduction

Tissue engineering allows the design and formation of new tissues in order to create biological substitutes capable of improving, repairing or curing the biological tissues present in the human body. Many strategies used in this area depend on the use of a material scaffold that acts as a synthetic extracellular matrix, organizes the cells into a 3D architecture and releases stimulating substances, which direct the growth and formation of the desired tissue.

In addition, it must be able to increase and diversify the cells and possess specific mechanical characteristics depending on the tissue to be regenerated: adequate mechanical properties, porosity and permeability to allow cell development.

Technical features

Patented invention related to the use of a recombinant protein scaffold for the preparation of cell culture plates to be used for the development of biomaterials for neuro regenerative medicine. The innovation consists of having a simple, practical and economic growth system for neuronal cells that does not require the use of growth factors, expensive and delicate.

Possible Applications

  • “Disposable” research materials;
  • Biocompatible materials for medical research and use.

Advantages

  • Innovative product in the field of “disposable” materials for neuronal cell cultures, of potential interest in the fields of neurobiology and neurophysiology;
  • Simplicity and practicality of use;
  • Industrially scalable and cost-effective production;
  • Low-cost, biocompatible scaffold for the “artificial tissues” market;
  • Potential use for medical neuronal tissue regeneration.