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PROCESS FOR THE PREPARATION OF BLOOD COMPONENT AND BIOMEDICAL DEVICE

Health technologyNeonatologyPersonalized MedicineRegenerative medicineTransfusion

Introduction

Device for processing umbilical cord blood into leucoreducated packed red blood cells in additive solution, platelets and platelet-poor plasma.

The transfusion of red blood cells from adult donors (which contain adult hemoglobin with high oxygen transfer capacity) to premature infants may contribute to causing oxidative complications including retinopathy of prematurity. This complication is less frequent in premature babies who have a high percentage of fetal hemoglobin during the first month of life (characterized by a lower ability to release oxygen).

Clinical interest arises from the fact that umbilical cord blood has biological characteristics different from adult blood and is therefore considered a precious material.

Technical features

The invention is a device for fractionating the blood collected from umbilical cord into three constituents: plasma, platelets and erythrocytes. Through this kit, three blood products, platelet-poor plasma, platelet concentrate and erythrocyte concentrate in additive solution, can be obtained. Each of them is a standardized product, with different and specific clinical indications.

Each of them is a standardized product, with different and specific clinical indications.

Until now, the processing of cord blood into blood produces, although based on the same principles as that of adult blood, was not possible, due to the absence of kits adaptable to small collected volumes.

Possible Applications

  • Laboratory;
  • Therapeutic use;
  • The use of blood transfusions;
  • Neonatal transfusion.

Advantages

  • Allow sfractionation into blood components (CB);
  • Faster and more efficient CB fractionation procedures;
  • Improved biomedical device for the production, storage and traceability  of CB.