Politecnico di Torino - Corso Duca degli Abruzzi, 24 - 10129 Torino, ITALY

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NANOCOMPOSITE HYDROGEL FOR RADIOTHERAPY

Health and medicineHydrogeloncologyPharmaceutic

Introduction

Multifunctional biomaterial consisting of a hydrogel that is administered through an injection directly into the tissue to be treated. The particular composition of the hydrogel allows a gradual release of nanoparticles in the tumor tissue.

 

Technical features

Actual treatments allows nanoparticles to be retained into tumor tissues between 1 and 3 days. So, more administrations are needed, and consequently the amount of nanoparticles to be used is higher than what effectively needed, resulting in possible toxic effects to patients.

The particular composition of the hydrogel allows a gradual release of nanoparticles in the tumor tissue, avoiding an excessive dispersion of the same, with the result of prolonging the useful time of action of the nanoparticles and therefore allowing the use of a smaller number of nanoparticles for the treatment .

The particular structure of the nanoparticles allows the simultaneous, and symbiotic, action of radiotherapy and hyperthermia, to maximize the effectiveness of treatment against cancer cells.

Possible Applications

  • Pharmaceutical applications;
  • Tumor treatment;
  • Radiotherapy;
  • Hyperthermia.

Advantages

  • Slow release of the nanoparticles and therefore decrease in the number of intra-tumoral applications;
  • The patented Hydrogel allows the simultaneous application of Radiotherapy and Hyperthermia;
  • The patented Hydrogel has a high biological compatibility;
  • Broad spectrum of application: the types of treatable tumors are diverse.