Politecnico di Torino - Corso Duca degli Abruzzi, 24 - 10129 Torino, ITALY

+39 011 090 6100 info@tech-share.it

METHOD FOR THE DETECTION OF Galpha15 PROTEIN AS A TUMORAL MARKER IN PANCREATIC CANCER

Early stage diagnosisG ProteinNon-invasive diagnosisPancreasTumoral marker

Introduction

The object of the present invention is to provide a non-invasive method suitable for a diagnosis of pancreatic cancer at an early stage, obtaining the result quickly and useful for providing prognostic indications during treatment and follow-up.

Technical features

A new method for the detection of the G alpha 15 protein which plays a key role as it transmits signals on the inner surface of the cell membrane. By mediating the signals they regulate the survival, transcription and mobility of cells. However, any mutations disable the correct functioning of these signals, leading the G proteins to be oncogenic. The new method developed to identify the values ​​of the G15 protein through a blood sample increases the level of sensitivity with a reduction in timing. Current diagnostic methods of pancreatic cancer are invasive and use endoscopy, radiology and biopsy to collect the cells but are nevertheless unable to detect small tumors or identify anatomical variants of some forms of cancer. This simple blood sample will allow cancer to be detected at an early stage, also increasing the probability of survival since it often does not present any symptoms.

Possible Applications

  • Medical diagnostic test; by a simple blood  test it will be possible to diagnose pancreatic cancer;
  • Oncology: using a tumor marker it is possible to have the diagnose for pancreatic cancer diagnosis.

Advantages

  • High sensitivity;
  • Non invasive;
  • Early stage diagnosis;
  • Quick result test;
  • Low cost.