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DIAGNOSTIC KIT TO DISTINGUISH CROHN’S DISEASE FROM RECTOCOLITIS

Crohn’s diseaseDiagnostic KitInflammatory bowel disease IBDIntestinal tissue biopsyUlcerative colitis

Introduction

This patented kit can rapidly diagnose Crohn’s disease at an early stage, and distinguish it from Ulcerative Rectocolitis. This differentiation between the two inflammatory bowl diseases (IBD) is extremely important so that proper treatment is prescribed to patients, without causing unnecessary damage and treatment costs.

Technical features

Inflammatory bowl diseases (IBD) include Crohn’s disease and Ulcerative colitis. Currently, in order to distinguish them, diagnosis is based on laboratory, clinical, radiographic, endoscopic and histological examination. Unfortunately in 10-15% of patients that carry out a biopsy, the differentiation is not always clear, due to similar histological characteristics where the inflammation is located. The lack of specific and reliable markers able to distinguish between the two means that currently a globally recognized test method for the differentiated diagnosis of the two diseases does not exist. This often delays the administration of an effective therapy, thus increasing costs and decreasing patient welfare. This patented diagnostic kit on the other hand can identify Crohn’s disease with a specific marker that distinguishes it from other inflammatory bowl diseases.

Possible Applications

  • Diagnosis of Crohn’s disease with a precise distinction from Ulcerative rectocolitis or other IBDs starting from an inflamed intestinal tissue biopsy.

Advantages

  • Early stage diagnosis of Crohn’s diseases and precise differentiation form other inflammatory bowl diseases (IBD);
  • Reduces time and cost for treatment of IBDs.