Introduction

The present invention consists of a new interface (Liquid-EI, LEI) between a high-performance liquid chromatograph (LC) and a mass spectrometer equipped with electron ionization (EIMS). The device allows the analysis of a wide range of different low molecular weight molecules. The possibility to generate EI mass spectra provides the identification and quantification of the analytes in various matrices for a wide range of applications (i.e. biomedical, environmental, food, forensic, drugs of abuse).

Technical features

The present invention consists of a new interface (Liquid-EI, LEI) between a high-performance liquid chromatograph (LC) and a mass spectrometer equipped with electron ionization (EIMS). The device allows the analysis of a wide range of different low molecular weight molecules. The possibility to generate EI mass spectra provides the identification and quantification of the analytes in various matrices for a wide range of applications (i.e. biomedical, environmental, food, forensic, drugs of abuse).

Possible Applications

• Environmental contaminats;
• Food safety;
• Drugs of abuse;
• Metabolites, biomarkers, and pharmaceuticals;
• Real time monitoring of chemistry reactions.

Advantages

• Analysis of a wide range of low molecular weights molecules;
• Easy to use device;
• No matrix effects drawbacks;
• No polarity limitations;
• Low-manteinance costs.