Co.Di Technique for production of human cartilage
Animal modelReconstruction of the noseSolid cartilageTracheal cartilage
Introduction
The CoDi technique allows to produce solid human cartilage; using 1cm2 of chiondrocites it is possible to obtain 1 cm3 of mature solid cartilage, biocompatible.

Technical features
Cell cultures of human chondrocytes, taken from human hyaline cartilage, are grown in the laboratory and then implanted on a biocompatible scaffold which on the animal model form a 1 cm3 cube of biocompatible human solid cartilage.
Possible Applications
Solid cartilage can be used in reconstructive surgery of :
- the nose;
- the earpiece;
- the lower eyelid;
- and the trachea.
Advantages
- The solid cartilage is biocompatible;
- Cell kits are available at low cost;
- The procedure is easily reproducible;
- It is possible to produce solid cartilage of the desired size and shape.