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Antimicrobial dental adhesive graphene-based

Antimicrobial adhesiveCavityDental restorationEtch and rinse adhesiveFunctional rehabilitation


The patent is based on a dental adhesive with antimicrobial and anti-biofilm properties taking advantage of the use of graphene-based micro and nanometer fillers. The nanomaterials introduced into an adhesive are uniformly dispersed, without agglomerations inside the polymer and partially exposed over the adhesive surface. These significantly inhibit, by mechanical action, adhesion and bacterial growth.

Technical features

The adhesive object of the patent consists of a dental adhesive composed of BisGMA, filled with graphene-based nanoplachets (GNP), produced at low cost by thermal expansion, or its derivatives incorporated in the polymer matrix. Adhesives have strong antimicrobial properties against the bacteria that typically populate the oral cavity, such as Streptococcus mutants. Current commercial adhesives use nanometric fillers, in particular barium glass, zirconium oxide, aluminum oxide, or silicon dioxide, for the sole purpose of increasing the micromechanical adhesion between the adhesive and dentin or enamel, and therefore typically do not have specific properties. antimicrobials. The antimicrobial dental adhesives used have limitations, as organic fillers tend to worsen the mechanical characteristics of dental materials. In fact, these fillers are subject to shrinkage after the cure and polymerization phase, just like the matrix and therefore limit the mechanical strength of the composite.

Possible Applications

  • Dental adhesive with antimicrobial properties.


  • The particular production process of the new adhesive possess antimicrobial properties;
  • The production of this adhesive does not require structural changes to companies producing dental adhesives;
  • GNP possess the properties of the basal plane typical of 2D graphene, at a lower cost and without its technological problems. Moreover they can be used on a large scale.