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A FIELD EFFECT TRANSISTOR SENSOR AND A CORRESPONDING ARRAY DEVICE

BiopsyBiosensors arrayElectrolyte gated transistorSingle molecule detectiontransistor

Introduction

The aim of the invention is to provide a field effect transistor biosensor, which is mechanically and electrically stable and which is suitable for clustering in an easily fabricated low-cost structure.

Technical features

The proposed system works in a very similar way to an ELISA microplate with the same multifunction but the transduction system is based on a field effect transistor. The diagram is designed in such a way as to have total control over the characteristics of the device ensuring its stability in an aqueous environment and therefore the reliability of the performance of the device at the level of the single molecule. In particular, in addition to the biofunctional gate, a second reference gate is inserted to ensure the stability of the device. It is designed for application in high performance clinical analyzes, such as ultraselective liquid biopsies, and can replace invasive analyzes on diseased tissues. Existing techniques are expensive and time-consuming.

Possible Applications

  • Screening of tumor markers;
  • Early diagnosis of neurodegenerative diseases;
  • Multi-modal biomarker assays.

Advantages

  • Stability in water and in time;
  • High sensitivity;
  • Allows the disclosure of more than one marker;
  • Low cost.